MediPrint Ophthalmics Announces Promising Results from Its SIGHT-2 Phase 2b Group 1 Clinical Study
Benzinga Human Trial with Novel Glaucoma Treatment Rendered a Clinically Meaningful Efficacy Outcome and Positive Safety and Tolerability Data
Today, MediPrint Ophthalmics (MediPrint), an emerging San Diego-based clinical stage eye care pharmaceutical company focused on enhancing vision for life, announces it has completed its SIGHT-2 dose-finding Phase 2b Group 1 (low dose) study for its proprietary drug-eluting contact lens for glaucoma. This is the first of potentially three doses in the second study of its clinical program SIGHT (Sustained Innovative Glaucoma and ocular Hypertension Treatment) for LL-BMT1, a preservative-free weekly medicated contact lens releasing bimatoprost to treat open angle glaucoma and ocular hypertension. SIGHT-2 is designed to assess dose optimization for the Company's lead asset, LL-BMT1, and was preceded by the successful completion of the Company's SIGHT-1 study that validated the MediPrint process and contact lenses for treating human subjects.
In the SIGHT-2 Group 1 study, MediPrint's LL-BMT1 (low dose) was administered to 11 patients, whose average age was 52.0 years old and who had not previously worn contact lenses, for a duration of three (3) weeks. The study subjects wore a new LL-BMT1 (low dose) lens in each eye for seven (7) days continuously for three (3) consecutive weekly lens insertion cycles (21 days total). There was also a reference arm in the clinical trial in which the study subjects used timolol 0.5% topical eye drops twice a day for three (3) weeks.
